Methandrosterone

2024-05-16by admin

Methandrosterone Structural Formula

Structural formula

Business number 01H7
Molecular formula C20H28O2
Molecular weight 300.44
label

Methandrostenone,

Dehydrotestosterone,

Dehydromethyltestosterone,

17BETA-Hydroxy-17-methylestro-1,4-dien-3-one,

Testosterone,

1-Dehydro-17α-methyltestosterone,

Dianabol,

Methandienone,

Methandrostenolone

Numbering system

CAS number:72-63-9

MDL number:MFCD00003650

EINECS number:200-787-2

RTECS number:BV8000000

BRN number:2056255

PubChem number:24879519

Physical property data

1. Character:White or slightly yellow crystal powder, odorless


2. Density (g/mL,25/4): Unsure


3. Relative vapor density (g/mL,AIR=1): Unsure


4. Melting point (ºC):165 -166


5. Boiling point (ºC,Normal pressure): Uncertain


6. Boiling point (ºC, 5.2 kPa): Unsure


7. Refractive index:Not sure


8. Flash Point (ºC): Unsure


9. Specific optical rotation (º): Unsure


10. Autoignition point or ignition temperature (ºC): Unsure


11. Vapor pressure (kPa,25 ºC): Unsure


12. Saturated vapor pressure (kPa,60 ºC): Unsure


13. Heat of combustion (KJ/mol): Unsure


14. Critical temperature (ºC): Unsure


15. Critical pressure (KPa): Unsure


16. Oil and water (octanol/Log value of the partition coefficient of water: Uncertain


17. Explosion limit (%,V/V): Unsure


18. Lower explosion limit (%,V/V): Unsure


19. Solubility:Almost insoluble in water, soluble in ethanol, chloroform, slightly soluble in ether

Toxicological data

Acute toxicity: Rat oral LD50: >1 mg/kg; Rat intraperitoneal LD50425 mg/kg;
Oncogenic: MaleOral SutraTDLo561 mg/kg/7Y-C;
Reproduction: Male Oral PeriodTDLo13 mg/kgSEX/DURATION : male 60 day(s) pre-mating;
 Rat oral narcosisTDLo200 mg/kgSEX/DURATION: female 10 day(s) pre-mating;
Rat oral passageTDLo200 mg/kgSEX/DURATION: male 10 day(s) pre-mating;
Subcutaneous injection in ratsTDLo7 mg/kgSEX/DURATION: female 14 day(s) pre-mating;
Mutagenic: Mouse oral Display Sexual Death Test 200 mg/kg/10D (Intermittent);

Ecological data

None

Molecular structure data

1. Molar refractive index:87.68


2. Molar volume (m3/mol):266.3


3. isotonic specific volume (90.2K):689.6


4. Surface Tension (dyne/cm):44.9


5. Polarizability(10-24cm3):34.76

Compute chemical data

1. Hydrophobic parameters Calculate reference value (XlogP):3.6


2. Hydrogen Bonding Number of donors: 1


3. Hydrogen Bonding Number of receptors: 2


4. Rotatable Number of chemical bonds: 0


5. Interchange Number of isomers: 3


6. Topological molecular polar surface area ( TPSA):37.3


7. Heavy atoms Quantity: 22


8. Surface charge :0


9. Complexity :589


10. Isotope atomic number:0


11. Determine the number of atomic stereocenters:6


12.   Number of uncertain atomic stereocenters:0


13. Determine the number of stereocenters of chemical bonds:0


14. Uncertain number of chemical bond stereocenters:0


15. Number of covalent bond units: 1

Properties and stability

None

Storage method

None

Synthesis method

Prepared from sisal saponin as raw material

Purpose

Used for osteoporosis, recovery period of chronic wasting disease, severe infection, burns, etc. Negative nitrogen balance, promotes the growth of premature infants and immature infants, etc. In addition, it can also be used for fractures that are not easy to heal, hypercholesterolemia, postpartum weakness, etc. The preparation is a tablet.


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